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Test ID: FCAH1    
CAH Pediatric Profile 1, 21-OH Deficiency Screen (Androstene- dione, Cortisol, DHEA, 17-OH-Progesterone, Testosterone)

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Androstenedione, Mass Spec

     Units:  ng/dL

Age                                                      Range

Premature (26-28w) Day 4                      63-935

Premature (31-35w) Day 4                      50-449

Full Term (1-7 days)                            <10-279

           

Levels decrease rapidly to <52 ng/dL after one week.

1m-11m                                               <10-37

           

Androstenedione gradually decreases during the first six

months to prepubertal levels.

           

Prepubertal Children                              <10-17

Adult Males                                             44-186

Adult Females                                         28-230

Females Postmenopausal                      <10-93

 

Females

Tanner Stages               Age (years)        Range

          1                          <9.2                 <10-17

          2                         9.2-13.7            <10-72

          3                         10.0-14.4             50-170

          4                         10.7-15.6             47-208

          5                         11.8-18.6             50-224

 

Males

Tanner Stages               Age (years)        Range

          1                          <9.8                  <10-17

          2                           9.8-14.5          <10-33

          3                         10.7-15.4              17-72

          4                         11.8-16.2              15-115          

          5                         12.8-17.3              33-192

 

Cortisol, Serum or Plasma

     Units:  ug/dL

Age                                                      Range

Premature (26-28w) Day 4                      1.0 - 11

Premature (31-35w) Day 4                      2.5 -   9.1

Full Term Day 3                                     1.7 - 14

Full Term Day 7                                     2.0 - 11

 

31d - 11m                                             2.8 - 23

12m - 15y (8:00 AM)                              3.0 - 21

 

Adults

   8:00 AM                                             8.0 - 19

   4:00 PM                                             4.0 - 11

 

Dehydroepiandrosterone (DHEA), Serum

     Units:  ng/dL

Age                                      Range

1-5 yrs                                               <68

6-7 yrs                                               <111

8-10 yrs                                             <186

11-12 yrs                                           <202

13-14 yrs                                           <319

15-16 yrs                                          39-481

17-19 yrs                                          40-491

20-49 yrs                                          31-701

> or = 50 yrs                                     21-402        

 

17-Alpha-Hydroxyprogesterone, Serum

     Units:  ng/dL    

 Age                                                     Range            

Premature (26-28w) Day 4                    124 - 841

Premature (31-35w) Day 4                      26 - 568

 

Full-Term Day 3                                    <78

 

Males: Levels increase after the first week to peak values

ranging from 40 - 200 between 30 and 60 days. Values then

decline to a prepubertal value of <91 before one year.

 

      Prepubertal                                     <91     

     Adult Males                                    27 - 199

Females

      1 - 11m                                         13 - 106

      Prepubertal                                     <91

Adult Females

      Follicular                                       15 - 70

      Luteal                                           35 - 290

 

Females

Tanner Stages               Age (years)       Range

          1                          <9.2                  <83

          2                         9.2-13.7            11-98

          3                         10.0-14.4           11-155

          4                         10.7-15.6           18-230

          5                         11.8-18.6           20-265

 

Males

Tanner Stages               Age (years)         Range

          1                          <9.8                    <91

          2                            9.8-14.5            <116

          3                         10.7-15.4             10-138

          4                         11.8-16.2             29-180

          5                         12.8-17.3             24-175

 

Testosterone, Serum (Total)

     Units:  ng/dL         

 Age                                                     Range

Males                                 

  Premature (26-28w) Day 4                    59 - 125

  Premature (31-35w) Day 4                    37 - 198

  Newborns                                           75 - 400

 

1 - 7m:  Levels decrease rapidly the first week to 20 - 50, then

increase to 60 - 400 between 20 - 60 days. Levels then decline

to prepubertal range levels of <2.5 - 10 by seven months.

 

Females

  Premature (26 - 28w) Day 4                  5 - 16

  Premature (31 - 35w) Day 4                  5 - 22

  Newborns                                          20 - 64

 

1 - 7m: Levels decrease during the first month to less than 10

and remain there until puberty.

 

Prepubertal Males and Females             <2.5 - 10

Adult Males >18 years                           348 - 1197

Adult Females                                                  

            Premenopausal:                          10 - 55

            Postmenopausal:                          7 - 40

 Males

Tanner Stage           Age (years)            Male

      1                                 <9.8         <2.5 – 10

      2                           9.8 – 14.5          18 – 150

      3                         10.7 – 15.4         100 – 320

      4                         11.8 – 16.2         200 – 620

      5                         12.8 – 17.3         350 – 970

 

Females

Tanner Stage          Age (years)              Female

      1                              <9.2               <2.5 – 10

      2                            9.2 – 13.7            7 – 28

      3                          10.0 – 14.4           15 – 35

      4                          10.7 – 15.6           13 – 32

      5                          11.8 – 18.6            20 - 38

 

Test Performed by:   Esoterix Endocrinology

                                4301 Lost Hills Rd

                                Calabasas Hills, CA 91301