Test ID: FFES
Estradiol Free, Serum (includes Estradiol and SHBG)
Reference Values 
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Free Estradiol, Percent
Reference Ranges (%)
Age Range
Adult Males 1.7 - 5.4
Adult Females 1.6 - 3.6
Free Estradiol, Serum
Reference Ranges (pg/mL)
Age Range
Adult Males 0.2 - 1.5
Adult Females 0.6 - 7.1
Sex Hormone Binding Globulin (SHBG), Serum
Reference Ranges (nmol/L)
Age Range
1 - 23m 60 - 252
Prepubertal (24m - 8y) 72 - 220
Pubertal
Males 16 - 100
Females 36 - 125
Adult Males 20 - 60
Adult Females
Premenopausal 40 - 120
Postmenopausal 28 - 112
Estradiol, Serum
Reference Ranges (pg/mL)
Age Range
Newborn Levels are markedly elevated at birth and fall rapidly during the first week to prepubertal values of <15
Males <6m Levels increase to 10 - 32 between 30 and 60 days, hen decline to prepubertal levels of <15 by six months.
Females <1y Levels increase to 5.0 - 50 between 30 and 60 days, then decline to prepubertal levels of <15 during the first year.
Prepubertal <15
Adult Males 8.0 - 35
Adult Females
Follicular 30 - 100
Luteal 70 - 300
Postmenopausal <15
Test Performed By: Esoterix Endocrinology
4301 Lost Hills Road
Calabasas Hills, CA 91301
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