Test ID: FPAP2
Premature Adrenarche Profile II (Androstenedione, DHEA, 17-OH- Pregnenolone, 17-Alpha-Hydroxyprogesterone, Testosterone)
Reference Values 
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Androstenedione, Mass Spec
Units: ng/dL
Age Range
Premature (26-28w) Day 4 63-935
Premature (31-35w) Day 4 50-449
Full Term (1-7 days) <10-279
Levels decrease rapidly to <52 ng/dL after one week.
1-11m <10-37
Androstenedione gradually decreases during the first
six months to prepubertal levels.
Prepubertal Children: <10-17
Adult Males 44-186
Adult Females 28-230
Females Postmenopasual <10-93
Females
Tanner Stages Age (years) Range
1 <9.2 <10-17
2 9.2-13.7 <10-72
3 10.0-14.4 50-170
4 10.7-15.6 47-208
5 11.8-18.6 50-224
Males
Tanner Stages Age (years) Range
1 <9.8 <10-17
2 9.8-14.5 <10-33
3 10.7-15.4 17-72
4 11.8-16.2 15-115
5 12.8-17.3 33-192
Dehydroepiandrosterone (DHEA)
Units: ng/dL
Age Range
1-5 yrs <68
6-7 yrs <111
8-10 yrs <186
11-12 yrs <202
13-14 yrs <319
15-16 yrs 39 - 481
17-19 yrs 40 - 491
20-49 yrs 31 - 701
> or = 50 yrs 21 - 402
17-OH Pregnenolone, Mass Spec
Units: ng/dL
Age Range
Premature (26-28w) Day 4 375 - 3559
Premature (31-35w) Day 4 64 - 2380
3 Days 10 - 829
1 - 5m 36 - 763
6 - 11m 42 - 540
12 - 23m 14 - 207
24m-5y 10 - 103
6 - 9y 10 - 186
Pubertal 44 - 235
Adults 53 - 357
17-Alpha-Hydroxyprogesterone
Units: ng/dL
Age Range
Premature (26-28w) Day 4 124 - 841
Premature (31-35w) Day 4 26 - 568
Full-Term Day 3 <78
Males
Levels increase after the first week to peak values ranging from
40-200 ng/dL between 30 and 60 days. Values then decline to a
prepubertal value of <91 before one year.
Prepubertal <91
Adult Males 27 - 199
Females
(1 - 11 Months) 13 - 106
Prepubertal <91
Adult Females
Follicular 15 - 70
Luteal 35 - 290
Females
Tanner Stages Age (years) Range
1 <9.2 <83
2 9.2-13.7 11-98
3 10.0-14.4 11-155
4 10.7-15.6 18-230
5 11.8-18.6 20-265
Males
Tanner Stages Age (years) Range
1 <9.8 <91
2 9.8-14.5 <116
3 10.7-15.4 10-138
4 11.8-16.2 29-180
5 12.8-17.3 24-175
Testosterone, Serum (Total)
Units:ng/dL
Age Range
Males
Premature (26-28w) Day 4 59 -125
Premature (31-35w) Day 4 37 -198
Newborns 75 - 400
1 - 7m: Levels decrease rapidly the first week to 20-50, then
increase to 60-400 between 20-60 days. Levels then decline to
prepubertal range levels of <2.5 - 10 by seven months.
Females
Premature (26 - 28w) Day 4 5 - 16
Premature (31 - 35w) Day 4 5 - 22
Newborns 20 - 64
1 - 7m: Levels decrease during the first month to less than 10
and remain there until puberty.
Prepubertal Males and Females <2.5 - 10 ng/dL
Adult Males >18 years 348 - 1197
Adult Females
Premenopausal: 10 - 55
Postmenopausal: 7 - 40
Males
Tanner Stage Age (years) Male
1 <9.8 <2.5 - 10
2 9.8 - 14.5 18 - 150
3 10.7 - 15.4 100 - 320
4 11.8 - 16.2 200 - 620
5 12.8 - 17.3 350 - 970
Females
Tanner Stage Age (years) Female
1 <9.2 <2.5 - 10
2 9.2 - 13.7 7 - 28
3 10.0 - 14.4 15 - 35
4 10.7 - 15.6 13 - 32
5 11.8 - 18.6 20 - 38
Test Performed By: Esoterix Endocrinology
4301 Lost Hills Road
Calabasas Hills, CA 91301
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