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Test ID: FPAP2    
Premature Adrenarche Profile II (Androstenedione, DHEA, 17-OH- Pregnenolone, 17-Alpha-Hydroxyprogesterone, Testosterone)

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

 

Androstenedione, Mass Spec

  Units: ng/dL

Age                                          Range

Premature (26-28w)  Day 4         63-935

Premature (31-35w)  Day 4         50-449

Full Term (1-7 days)                <10-279

 

Levels decrease rapidly to <52 ng/dL after one week.

 

1-11m                                     <10-37

 

Androstenedione gradually decreases during the first

six months to prepubertal levels.

 

Prepubertal Children:                <10-17

Adult Males                               44-186

Adult Females                           28-230

Females Postmenopasual        <10-93

 

Females

Tanner Stages               Age (years)        Range

          1                          <9.2                 <10-17

          2                         9.2-13.7            <10-72

          3                       10.0-14.4               50-170

          4                       10.7-15.6               47-208

          5                       11.8-18.6               50-224

 

Males

Tanner Stages               Age (years)         Range

          1                          <9.8                  <10-17

          2                            9.8-14.5         <10-33

          3                         10.7-15.4              17-72

          4                         11.8-16.2              15-115          

          5                         12.8-17.3              33-192

 

Dehydroepiandrosterone (DHEA)

   Units: ng/dL

Age                                          Range

1-5 yrs                                        <68

6-7 yrs                                       <111

8-10 yrs                                     <186

11-12 yrs                                    <202

13-14 yrs                                    <319

15-16 yrs                                  39 - 481

17-19 yrs                                  40 - 491

20-49 yrs                                  31 - 701

> or = 50 yrs                             21 - 402        

 

17-OH Pregnenolone, Mass Spec

    Units: ng/dL

Age                                          Range                         

Premature (26-28w)  Day 4        375 - 3559

Premature (31-35w)  Day 4          64 - 2380

3 Days                                      10 - 829

1 - 5m                                        36 - 763

6 - 11m                                      42 - 540

12 - 23m                                   14 - 207

24m-5y                                      10 - 103

6 - 9y                                        10 - 186

Pubertal                                     44 - 235

Adults                                        53 - 357

 

17-Alpha-Hydroxyprogesterone

   Units: ng/dL    

 Age                                         Range     

Premature (26-28w)  Day 4       124 - 841

Premature (31-35w)  Day 4         26 - 568

Full-Term Day 3                          <78

 

Males                                    

Levels increase after the first week to peak values ranging from

40-200 ng/dL between 30 and 60 days. Values then decline to a

prepubertal value of <91 before one year.

Prepubertal                              <91

Adult Males                            27 - 199

Females

(1 - 11 Months)                       13 - 106

Prepubertal                               <91

Adult Females

      Follicular                          15 - 70

      Luteal                               35 - 290

 

Females

Tanner Stages               Age (years)       Range

          1                          <9.2                  <83

          2                         9.2-13.7            11-98

          3                         10.0-14.4           11-155

          4                         10.7-15.6           18-230

          5                         11.8-18.6           20-265

 

Males

Tanner Stages               Age (years)       Range

          1                          <9.8                    <91

          2                            9.8-14.5           <116

          3                         10.7-15.4             10-138

          4                         11.8-16.2             29-180

          5                         12.8-17.3             24-175

 

Testosterone, Serum (Total)  

     Units:ng/dL       

 Age                                         Range

Males                                 

Premature (26-28w) Day 4           59 -125

Premature (31-35w) Day 4           37 -198

Newborns                                 75 - 400

1 - 7m: Levels decrease rapidly the first week to 20-50, then

increase to 60-400 between 20-60 days. Levels then decline to

prepubertal range levels of <2.5 - 10 by seven months.

 

Females

Premature (26 - 28w)  Day 4          5 - 16

Premature (31 - 35w)  Day 4          5 - 22

Newborns                                   20 - 64

1 - 7m: Levels decrease during the first month to less than 10

and remain there until puberty.

 

Prepubertal Males and Females             <2.5 - 10 ng/dL

 

Adult Males   >18 years             348 - 1197

Adult Females                                                  

            Premenopausal:              10 - 55

            Postmenopausal:              7 - 40

 

Males

Tanner Stage           Age (years)                   Male

      1                              <9.8                   <2.5 - 10

      2                         9.8 - 14.5                   18 - 150

      3                       10.7 - 15.4                 100 - 320

      4                       11.8 - 16.2                 200 - 620

      5                       12.8 - 17.3                 350 - 970

 

Females

Tanner Stage          Age (years)              Female

      1                          <9.2                    <2.5 - 10

      2                        9.2 - 13.7                7 - 28

      3                      10.0 - 14.4               15 - 35

      4                      10.7 - 15.6               13 - 32

      5                      11.8 - 18.6               20 - 38

 

Test Performed By:  Esoterix Endocrinology

                               4301 Lost Hills Road

                               Calabasas Hills, CA 91301