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Test ID: FCAH6    
CAH Pediatric Profile 6, Comprehensive Screen (Androstenedione, Specific S, Cortisol, DHEA, DOC, 17-OH-Prenenolone, Progesterone, 17-OH-Progesterone, Testosterone)

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Androstenedione

     Units:  ng/dL

Age                                              Range

Premature (26-28w) Day 4             63 - 935

Premature (31-35w) Day 4             50 - 449

Full Term (1-7 days)                    <10 - 279

           

Levels decrease rapidly to a range of <52 ng/dL after one week.

 

1-11m                                         <10 - 37

           

Androstenedione gradually decreases during the first six

months to prepubertal levels.

           

Prepubertal Children                     <10-17

Adult Males                                    44 - 186

Adult Females                                28 - 230

Females Postmenopausal            <10-93

Females

Tanner Stages               Age (years)        Range

          1                          <9.2                 <10-17

          2                         9.2-13.7            <10-72

          3                         10.0-14.4             50-170

          4                         10.7-15.6             47-208

          5                         11.8-18.6             50-224

 

Males

Tanner Stages               Age (years)        Range

          1                          <9.8                  <10-17

          2                            9.8-14.5         <10-33

          3                         10.7-15.4             17-72 

          4                         11.8-16.2             15-115           

          5                         12.8-17.3             33-192

 

 

Cortisol

     Units:  ug/dL

Age                                                      Range

Premature (26-28w) Day 4                      1.0 - 11

Premature (31-35w) Day 4                      2.5 -   9.1

Full Term Day 3                                     1.7 - 14

Full Term Day 7                                     2.0 - 11

31d - 11m                                             2.8 - 23

12m - 15y (8:00 AM)                              3 .0 - 21

 

Adults

   8:00 AM                                             8.0 - 19

   4:00 PM                                             4.0 - 11

 

 

Deoxycorticosterone (DOC)

     Units:  ng/dL

Age                                                      Range

Premature (26 - 28w) Day 4                    20 - 105

Premature (34 - 36w) Day 4                    28 - 78

Newborn:   Levels are markedly elevated at birth and

decrease rapidly during the first week to the range of

7 - 49 as found in older infants.

    

1 - 11m                                                 7 - 49

Prepubertal Children                              2 - 34

Pubertal Children

   and Adults 8:00 AM                            2 – 19

 

 

Dehydroepiandrosterone (DHEA)

     Units:  ng/dL

Age                                                 Range

 1-5 yrs                                               <68

6-7 yrs                                               <111

8-10 yrs                                             <186

11-12 yrs                                           <202

13-14 yrs                                           <319

15-16 yrs                                           39-481

17-19 yrs                                           40-491

20-49 yrs                                           31-701

> or = 50 yrs                                     21-402      

 

11-Desoxycortisol

     Units:  ng/dL

Age                                                   Range

Premature (26-28w) Day 4                 110 - 1376

Premature (31-35w) Day 4                   48 - 579

Newborn Day 3                                  13 - 147

1 - 11m                                            <10 - 156

Prepubertal 8:00 AM                           20 - 155

Pubertal Children and

Adults 8:00 AM                                  12 - 158

 

17-OH Pregnenolone

      Units:  ng/dL

Age                                                  Range                              

Premature (26-28w) Day 4                375 - 3559

Premature (31-35w) Day 4                 64 - 2380

3 Days                                            10 - 829

1 - 5m                                             36 - 763

6 - 11m                                            42 - 540

12 - 23m                                         14 - 207

24m  - 5y                                        10 - 103

6 - 9y                                              10 - 186

Pubertal                                          44 - 235

Adults                                             53 - 357

 

 Progesterone

     Units:  ng/dL

Males

Age                                          Range                    

1-16y                                       <10-15

Adults                                      <10-11

 

Females

Age                                          Range                    

1-10y                                       <10-26

    11y                                      <10-255

    12y                                      <10-856

    13y                                      <10-693

    14y                                      <10-1204

    15y                                      <10-1076

    16y                                      <10-1294

 

Adult

Cycle Days                                  Range

1-6                                             <10-17

7-12                                           <10-135

13-15                                          <10-1563

16-28                                          <10-2555

Post Menopausal                        <10

 

Note: Luteal progesterone peaked from 350 to 3750 ng/dL

on days ranging from 17 to 23.

 

17-Alpha-Hydroxyprogesterone

     Units:  ng/dL    

 Age                                             Range            

Premature (26-28w) Day 4             124 - 841

Premature (31-35w) Day 4               26 - 568

 Full-Term Day 3                               <78

 

Males: Levels increase after the first week to peak values

ranging from 40 - 200 between 30 and 60 days. Values then

decline to a prepubertal value of  <91 before one year.

 

      Prepubertal                             <91

     Adult Males                               27-199

Females

      1 - 11m                                    13-106

      Prepubertal                             <91

Adult Females

      Follicular                                  15-70

      Luteal                                       35-290

 

Females

Tanner Stages               Age (years)       Range

          1                          <9.2                  <83

          2                         9.2-13.7            11-98

          3                         10.0-14.4           11-155

          4                         10.7-15.6           18-230

          5                         11.8-18.6           20-265

 

Males

Tanner Stages               Age (years)       Range

           1                          <9.8                 <91

          2                           9.8-14.5            <116

          3                         10.7-15.4             10-138

          4                         11.8-16.2             29-180

          5                         12.8-17.3             24-175

 

Testosterone, Serum (Total)

     Units:  ng/dL         

 Age                                                     Range

Males                                 

  Premature (26-28w) Day 4                    59 - 125

  Premature (31-35w) Day 4                    37 - 198

  Newborns                                           75 - 400

 

1 - 7m:  Levels decrease rapidly the first week to 20 - 50, then

increase to 60 - 400 between 20 - 60 days. Levels then decline

to prepubertal range levels of <2.5 - 10 by seven months.

 

Females

  Premature (26 - 28w) Day 4                  5 - 16

  Premature (31 - 35w) Day 4                  5 - 22

  Newborns                                          20 - 64

 

1 - 7m: Levels decrease during the first month to less than 10

and remain there until puberty.

 

Prepubertal Males and Females           <2.5 - 10

Adult Males    >18 years                      348 - 1197

Adult Females                                                  

    Premenopausal:                             10 - 55

    Postmenopausal:                             7 - 40

 

Males

Tanner Stage           Age (years)             Male

      1                           <9.8                 <2.5 - 10

      2                           9.8 – 14.5           18 - 150

      3                         10.7 – 15.4          100 - 320

      4                         11.8 – 16.2          200 - 620

      5                         12.8 – 17.3          350 - 970

 

Females

Tanner Stage          Age (years)             Female

      1                          <9.2                  <2.5 - 10

      2                       9.2 - 13.7                 7 - 28

      3                      10.0 - 14.4               15 - 35

      4                      10.7 - 15.6               13 - 32

      5                      11.8 - 18.6                20 - 38

 

Test Performed By:   Esoterix Endocrinology

                                4301 Lost Hills Rd

                                Calabasas Hills, CA 91301