FCAH6 - Clinical: CAH Pediatric Profile 6, Comprehensive Screen (Androstenedione, Specific S, Cortisol, DHEA, DOC, 17-OH-Prenenolone, Progesterone, 17-OH-Progesterone, Testosterone)

Test Catalog

Test ID: FCAH6    
CAH Pediatric Profile 6, Comprehensive Screen (Androstenedione, Specific S, Cortisol, DHEA, DOC, 17-OH-Prenenolone, Progesterone, 17-OH-Progesterone, Testosterone)

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Androstenedione

     Units:  ng/dL

Age                                                      Range

Premature (26-28w) Day 4                      63 - 935

Premature (31-35w) Day 4                      50 - 449

Full Term (1-7 days)                                <10 - 279

           

Levels decrease rapidly to a range of <52 ng/dL after one week.

 

1-11m                                                   <10 - 37

           

Androstenedione gradually decreases during the first six months to prepubertal levels.

           

Prepubertal Children                              <10-17

Adult Males                                           44 - 186

Adult Females                                       28 - 230

Females Postmenopausal                      <10-93

 

 

Cortisol

     Units:  ug/dL

Age                                                      Range

Premature (26-28w) Day 4                      1.0 - 11

Premature (31-35w) Day 4                      2.5 -   9.1

Full Term Day 3                                     1.7 - 14

Full Term Day 7                                     2.0 - 11

31d - 11m                                             2.8 - 23

12m - 15y (8:00 AM)                              3 .0 - 21

 

Adults

   8:00 AM                                             8.0 - 19

   4:00 PM                                             4.0 - 11

 

 

Deoxycorticosterone (DOC)

     Units:  ng/dL

Age                                                      Range

Premature (26 - 28w) Day 4                    20 - 105

Premature (34 - 36w) Day 4                    28 - 78

Newborn:   Levels are markedly elevated at birth and decrease rapidly during the first week to the range of 7 - 49 as found in older infants.

    

1 - 11m                                                 7 - 49

Prepubertal Children                              2 - 34

Pubertal Children

   and Adults 8:00 AM                            2 - 19

 

 

Dehydroepiandrosterone (DHEA)

     Units:  ng/dL

Age                                                        Range

Premature (26 - 31w)                               82 – 1484

Premature (32 - 35w)                              56 – 1853

Full Term (2 – 7d)                                  41 – 1292

8d - 5m                                                 <948

6 – 12m                                                <136

1-5 y                                                     <68

6-7 y                                                     <111

8-10 y                                                   <186

11-12 y                                                 <202

13-14 y                                                 <319

15-16 y                                                 39-481

17-19 y                                                 40-491

20-49 y                                                 31-701

> or = 50 y                                            21-402      

 

11-Desoxycortisol

     Units:  ng/dL

Age                                                      Range

Premature (26-28w) Day 4                      110 - 1376

Premature (31-35w) Day 4                      48 - 579

Newborn Day 3                                     13 - 147

1 - 11m                                                 <10 - 156

Prepubertal 8:00 AM                              20 - 155

Pubertal Children and

Adults 8:00 AM                                     12 - 158

 

17-OH Pregnenolone

      Units:  ng/dL

Age                                                      Range                              

Premature (26-28w) Day 4                      375 - 3559

Premature (31-35w) Day 4                      64 - 2380

3 Days                                                  10 - 829

1 - 5m                                                   36 - 763

6 - 11m                                                 42 - 540

12 - 23m                                               14 - 207

24m  - 5y                                              10 - 103

6 - 9y                                                    10 - 186

Pubertal                                                44 - 235

Adults                                                   53 - 357

 

 Progesterone

     Units:  ng/dL

Males

Age                                                      Range                    

1-16y                                                    <10-15

Adults                                                   <10-11

 

Females

Age                                                      Range                    

1-10y                                                    <10-26

    11y                                                   <10-255

    12y                                                   <10-856

    13y                                                   <10-693

    14y                                                   <10-1204

    15y                                                   <10-1076

    16y                                                   <10-1294

 

Adult

Cycle Days                                            Range

1-6                                                        <10-17

7-12                                                      <10-135

13-15                                                    <10-1563

16-28                                                    <10-2555

Post Menopausal                                  <10

 

Note: Luteal progesterone peaked from 350 to 3750 ng/dL on days ranging from 17 to 23.

 

17-Alpha-Hydroxyprogesterone

     Units:  ng/dL    

 Age                                                     Range            

Premature (26-28w) Day 4                      124 - 841

Premature (31-35w) Day 4                      26 - 568

Full-Term Day 3                                     <78

 

Males: Levels increase after the first week to peak values ranging from 40 - 200 between 30 and 60 days. Values then decline to a prepubertal value of <91 before one year.

 

Prepubertal                                           <91

Adult Males                                           27-199

 

Females

      1 - 11m                                           13-106

      Prepubertal                                      <91

Adult Females

      Follicular                                         15-70

      Luteal                                             35-290

 

Testosterone, Serum (Total)

     Units:  ng/dL         

 Age                                                     Range

Males                                 

Premature (26-28w) Day 4                      59 - 125

Premature (31-35w) Day 4                      37 - 198

Newborns                                             75 - 400

 

1 - 7m:  Levels decrease rapidly the first week to 20 - 50, then increase to 60 - 400 between 20 - 60 days. Levels then decline to prepubertal range levels of <2.5 - 10 by seven months.

 

Females

Premature (26 - 28w) Day 4                    5 - 16

Premature (31 - 35w) Day 4                    5 - 22

Newborns                                             20 - 64

 

1 - 7m: Levels decrease during the first month to less than 10 and remain there until puberty.

 

Prepubertal Males and Females             <2.5 - 10

Adult Males    >18 years                        348 - 1197

Adult Females                                      

    Premenopausal:                                10 - 55

    Postmenopausal:                              7 - 40

 

Males

Tanner Stage           Age (years)             Male

      1                        <9.8                      <2.5 - 10

      2                         9.8 - 14.5              18 - 150

      3                         10.7 - 15.4            100 - 320

      4                         11.8 - 16.2            200 - 620

      5                         12.8 - 17.3            350 - 970

 

Females

Tanner Stage          Age (years)             Female

      1                        <9.2                      <2.5 - 10

      2                       9.2 - 13.7                7 - 28

      3                      10.0 - 14.4               15 - 35

      4                      10.7 - 15.6               13 - 32

      5                      11.8 - 18.6                20 - 38