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Test ID: FCAH4    
CAH Pediatric Profile 4:  3B-HSD Deficiency Screen (Androsten- edione, Cortisol, DHEA, 17-OH-Pregnenolone, 17-OH-Proges- terone)

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Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Androstenedione

     Units:  ng/dL

Age                                                      Range

Premature (26-28w) Day 4                      63-935

Premature (31-35w) Day 4                      50-449

Full Term (1-7 days)                            <10-279

           

Levels decrease rapidly to <52 ng/dL after one week.

 

1m-11m                                                <10-37

 

Androstenedione gradually decreases during the first six

months to prepubertal levels.

           

Prepubertal Children                             <10-17

Adult Males                                           44-186

Adult Females                                       28-230

Females Postmenopausal                     <10-93

 

Females

Tanner Stages                 Age (years)       Range

          1                          <9.2                 <10-17

          2                         9.2-13.7            <10-72

          3                         10.0-14.4             50-170

          4                         10.7-15.6             47-208

          5                         11.8-18.6             50-224

Males

Tanner Stages               Age (years)          Range

          1                          <9.8                  <10-17

          2                            9.8-14.5         <10-33

          3                         10.7-15.4             17-72 

          4                         11.8-16.2             15-115           

          5                         12.8-17.3             33-192

 

Cortisol

     Units:  ug/dL

Age                                                      Range

Premature (26-28w) Day 4                      1.0 - 11

Premature (31-35w) Day 4                      2.5 -   9.1

Full Term Day 3                                     1.7 - 14

Full Term Day 7                                     2.0 - 11

 

31d - 11m                                             2.8 - 23

12m - 15y (8:00 AM)                              3 .0 - 21

 

Adults

   8:00 AM                                             8.0 - 19

   4:00 PM                                             4.0 - 11

 

Dehydroepiandrosterone (DHEA)

     Units:  ng/dL

Age                                        Range

1-5 yrs                                               <68

6-7 yrs                                               <111

8-10 yrs                                             <186

11-12 yrs                                           <202

13-14 yrs                                           <319

15-16 yrs                                           39-481

17-19 yrs                                           40-491

20-49 yrs                                           31-701

> or = 50 yrs                                     21-402        

 

17-OH Pregnenolone

      Units:  ng/dL

Age                                          Range                              

Premature (26-28w) Day 4          375 - 3559

Premature (31-35w) Day 4            64 - 2380

3 Days                                       10 - 829

1 - 5m                                         36 - 763

6 - 11m                                       42 - 540

12 - 23m                                     14 - 207

24m  - 5y                                    10 - 103

6 - 9y                                          10 - 186

Pubertal                                      44 - 235

Adults                                         53 - 357

 

17-Alpha-Hydroxyprogesterone

     Units:  ng/dL    

 Age                                              Range            

Premature (26-28w) Day 4             124 - 841

Premature (31-35w) Day 4               26 - 568

 

(if no age submitted):

Full-Term Day 3                               <78    

 

Males: Levels increase after the first week to peak values

ranging from 40 - 200 between 30 and 60 days. Values then

decline to a prepubertal value of <91 before one year.

 

      Prepubertal                                    <91     

     Adult Males                                    27 - 199

Females

      1 - 11m                                         13 - 106

      Prepubertal                                     <91

Adult Females

      Follicular                                       15 - 70

      Luteal                                           35 - 290

 

Females

Tanner Stages               Age (years)      Range

          1                          <9.2                  <83

          2                         9.2-13.7            11-98

          3                         10.0-14.4           11-155

          4                         10.7-15.6           18-230

          5                         11.8-18.6           20-265

Males

Tanner Stages               Age (years)          Range

          1                          <9.8                      <91

          2                            9.8-14.5              <116

          3                         10.7-15.4              10-138

          4                         11.8-16.2              29-180

           5                       12.8-17.3              24-175

 

 

Test Performed BY:  Esoterix Endocrinology

                                4301 Lost Hills Rd

                                Calabasas Hills, CA 91301