Sinemet , Serum/Plasma
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Reporting limit determined each analysis.
Synonym(s): Sinemet Constituent
Synonyms(s): Sinemet Constituent
Following a single oral dose of 100 mg Levodopa and 25 mg Carbidopa (conventional Sinemet tablet): Approximately 0.3 mcg Levodopa/mL and 0.05 mcg Carbidopa/mL plasma at 1 hour post dose. Average steady-state trough plasma levels in elderly patients following a regimen of Sinemet CR (50 mg Carbidopa and 200 mg Levodopa sustained release tablets) three times daily:
0.16 mcg Levodopa/mL
0.07 mcg Carbidopa/mL