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Test ID: FSINE    
Sinemet , Serum/Plasma

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Reporting limit determined each analysis.

 

Levodopa

   Synonym(s): Sinemet Constituent

 

Carbidopa

   Synonyms(s): Sinemet Constituent

  

Following a single oral dose of 100 mg Levodopa and 25 mg Carbidopa (conventional Sinemet tablet): Approximately 0.3 mcg Levodopa/mL and 0.05 mcg Carbidopa/mL plasma at 1 hour post dose. Average steady-state trough plasma levels in elderly patients following a regimen of Sinemet CR (50 mg Carbidopa and 200 mg Levodopa sustained release tablets) three times daily:

  0.16 mcg Levodopa/mL

  0.07 mcg Carbidopa/mL

Analysis by High Performance Liquid Chromatography (HPLC)

 

Test Performed By:            NMS Labs

                                                  3701 Welsh Rd

                                                  PO Box 433A
                                                  Willow Grove, PA 19090-0437