Gastric Inhibitory Polypeptide (GIP)
Gastric Inhibitory Peptide is a 43 amino acid peptide structurally related to Glucagon and Secretin and is found in the mucosa of upper intestine produced by K cells. GIP was originally detected as a factor inhibiting the secretion of gastric acid and Gastrin secretion. Its major action has now been determined to be a potent stimulant of B cells to release Insulin and is also known as Glucose-Dependent Insulinotropic Peptide. Exaggerated increases in GIP are noted after glucose administration to patients with Pancreatitis. This increase is also seen in patients with Diabetes Mellitus. GIP levels are decreased by Calcitonin. Elevated levels are present in cases of Verner-Morrison Syndrome.
Fasting: Up to 50 pg/ml
Postprandial: 110 - 720 pg/ml
Test Performed by: Inter Science Institute
944 West Hyde Park
Inglewood, CA 90302
No significant cautionary statements.