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Unit Code 90054:
Malaria Antibody Screen (P. falciparum, P. vivax, P. malariae, P. ovale), IFA

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Reference Values

Reference Range:  Pos  => 1:64   Neg  <1:64

      

     < 64 - Probably no recent clinical involvement with malaria

     => 64 - In U.S. citizens (brief exposure) may reflect

             recent infection; in some areas of the world, may

             be maximum titer demonstratable even in clinical cases.

      

     In U.S. citizens with brief exposure to infection, a

     PLASMODIUM FALCIPARUM titer of =>1:64 may reflect recent

     infection. Speciation of the infecting malaria parasite is

     made by using four IFA slides prepared with P. FALCIPARUM,

     P. VIVAX, P. MALARIAE and P. OVALE, respectively. Antibody

     titers in U.S. citizens rarely persist more than six (6)

     months after chemotherapeutic cure. Titers in people with

     prolonged exposure and in people native to malaria endemic

     areas may persist for years because of relapses.

     Due to the increased volume of diagnostic specimens and to

     maximize the use of our malaria slides, we now titrate

     specimens at dilutions of 1:16 and 1:64. We will report

     immunofluorescence results that react at  dilutions equal to

     or less than 1:16 as negative. Tests that react at a dilution of

     1:64 will be reported as positive. By eliminating the

     reactivity of specimens at a dilution of 1:4 we are not

     changing the sensitivity of the immunofluorescence test.

      

     Test Performed by: Parasitic Disease Consultants

                                            2177-J Flintstone Drive

                                            Tucker, GA 30084

 

      

     

 

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