HGNA - Clinical: Mercury, Nails

Test Catalog

Test Name

Test ID: HGNA    
Mercury, Nails

Useful For Suggests clinical disorders or settings where the test may be helpful

Detecting mercury exposure

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Once absorbed and circulating, mercury becomes bound to numerous proteins, including keratin. The concentration of mercury in nails correlates with the severity of clinical symptoms. If the nails can be segregated by length, such an exercise can be useful in identifying the time of exposure.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

0-15 years: not established

> or =16 years: 0.0-0.9 mcg/g of nails

Interpretation Provides information to assist in interpretation of the test results

Normally, nails contains <1 mcg/g mercury; any amount more than this indicates that exposure to more than normal amounts of mercury has occurred.

Clinical Reference Provides recommendations for further in-depth reading of a clinical nature

1. Marques R, Do’rea J, Bastos W, and Malm O. Changes in children hair-Hg concentrations during the first 5 years: Maternal, environmental and iatrogenic modifying factors. Regulatory Toxicology and Pharmacology 2007;49:17–24

2. Canuel R, de Grosbois S, Atikesse L, and Lucotte M. New Evidence on Variations of Human Body Burden of Methylmercury from Fish Consumption. Environ Health Perspect 2006;114:302–306

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test