FIBR - Clinical: Fibroblast Culture

Test Catalog

Take Our Survey

Test ID: FIBR    
Fibroblast Culture

Useful For Suggests clinical disorders or settings where the test may be helpful

A preliminary step in obtaining cultured cells for genetic testing

Genetics Test Information Provides information that may help with selection of the correct test or proper submission of the test request

Fibroblast culture for biochemical genetic testing only. The additional tests desired must be indicated on the request form that accompanies the specimen.

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, cryopreservation for biochemical studies will always be performed at an additional charge. However, for multiple assays on a patient utilizing the ordered fibroblast culture, only 1 culture is required regardless of the number of assays ordered. If viable cells are not obtained within 30 days, client will be notified. Mycoplasma screening will be performed on all successfully grown fibroblast cultures. If Mycoplasma is detected, all pending fibroblast clinical testing will be cancelled and the samples will be discarded.

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Cultures of skin fibroblasts are useful for specialized testing, which requires skin cells. These cells can be cultured and tested at Mayo Clinic or sent to external laboratories performing these specialized tests. In addition, cells are frozen for at least 3 years for potential future studies on cultured cells or for molecular genetic testing.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Not applicable

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Potential interfering factors:

-Lack of viable cells

-Bacterial contamination

-Failure to transport tissue in an appropriate media

-Excessive transport time

-Exposure of the specimen to temperature extremes (freezing or >30 degrees C)

-Improper packaging may result in broken or leaky specimen containers or contamination of specimens during transport

Clinical Reference Provides recommendations for further in-depth reading of a clinical nature

 


Key