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Diagnosis of chyluria (galacturia)
Chyle is lymphatic fluid that contains emulsified fats (chylomicrons). Chyle in the urine (chyluria) is the result of obstruction of lymph flow and rupture of lymphatic vessels into the renal tubules. Chyluria, also called galacturia, imparts a milky appearance to urine.
No lipoproteins present
This assay provides information regarding the fat content in urine fluid. Urinary cholesterol and triglyceride values are normally <10 mg/dL. High triglycerides in urine may indicate chyluria.
Ascorbic acid (Vitamin C) interferes with the cholesterol determination and, to a lesser degree, the triglyceride concentration. Ascorbic acid falsely decreases the cholesterol and triglyceride results.
Result can be falsely decreased in patients with elevated levels of N-acetyl-p-benzoquinone imine (NAPQI)-a metabolite of acetaminophen, N-acetylcysteine (NAC), and metamizole.
Diamond E, Schapira HE: Chyluria-a review of the literature. Urology 1985;26:427-431