Diagnosis of chyluria (galacturia)
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Chyle is lymphatic fluid that contains emulsified fats (chylomicrons). Chyle in the urine (chyluria) is the result of obstruction of lymph flow and rupture of lymphatic vessels into the renal tubules. Chyluria, also called galacturia, imparts a milky appearance to urine.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
No lipoproteins present
This assay provides information regarding the fat content in urine fluid. Urinary cholesterol and triglyceride values are normally <10 mg/dL. High triglycerides in urine may indicate chyluria.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Ascorbic acid (Vitamin C) interferes with the cholesterol determination and, to a lesser degree, the triglyceride concentration. Ascorbic acid falsely decreases the cholesterol and triglyceride results.
Result can be falsely decreased in patients with elevated levels of N-acetyl-p-benzoquinone imine (NAPQI)-a metabolite of acetaminophen, N-acetylcysteine (NAC), and metamizole.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
Diamond E, Schapira HE: Chyluria-a review of the literature. Urology 1985;26:427-431