Unit Code 80919:
Drug Abuse Survey with Confirmation, Evaluation 3, Urine
Useful For
Suggests clinical disorders or settings where the test may be helpful
Detecting drug abuse involving amphetamines, barbiturates,
benzodiazepines, cocaine, marijuana metabolite, opiates, and
phencyclidine (PCP).
This test is intended to be used in a setting where the test results
can be used definitively to make a diagnosis.
Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
#80919 "Drug Abuse Survey with Confirmation, Evaluation 3, Urine"
was designed to test for and confirm (by gas chromatography-mass
spectrometry [GC-MS]) the most common classes of drugs of abuse.
This test uses the screening technique described under #8248 "Drug
Abuse Survey, Urine," which involves immunologic testing for drugs
by class. All positive screening results are confirmed by GC-MS
and quantitated before a positive result is reported.
This test represents the coupling of #8248 "Drug Abuse Survey,
Urine" with an automatic confirmation of all positive results by the
definitive assay available and described elsewhere (e.g., #8257
"Amphetamines, Urine").
Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Negative
Screening cutoff concentrations
Amphetamines: 500 ng/mL
Barbiturates: 200 ng/mL
Benzodiazepines: 200 ng/mL
Cocaine (benzoylecgonine - cocaine metabolite): 300 ng/mL
Opiates: 300 ng/mL
Phencyclidine: 25 ng/mL
Tetrahydrocannabinol carboxylic acid: 20 ng/mL
This report is intended for use in clinical monitoring or
management of patients. It is not intended for use in
employment-related testing.
Interpretation
Provides information to assist in interpretation of the test results
A positive result indicates that the patient has used the drug(s)
detected in the recent past. See "Quick Reference Guide" in
Special Instructions for estimated windows of detection
(the length of time after last use that drug may be present in the
urine). See individual tests (e.g., #8257 "Amphetamines, Urine")
for more information.
For general information about drug testing, see
"Drug Testing: An Overview of Mayo Clinic Tests Designed for Detecting Drug Abuse"
at www.MayoMedicalLaboratories.com.
Creatinine and specific gravity are measured as indicators of
specimen dilution.
Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Not intended for use in employment-related testing.
The test does not screen for drug classes other than those listed
above. More comprehensive screening is available using the
plasma or urine drug screens (#8421 "Drug Screen, Prescription/OTC,
Plasma" or #88760 "Drug Screen, Prescription/OTC, Urine").
For situations where chain-of-custody is required, a Chain-of-
Custody Kit (Supply T282) is available.
Clinical Reference
Provides recommendations for further in-depth reading of a clinical nature
Porter WF, Moyer TP: Clinical toxicology. In Tietz Textbook of
Clinical Chemistry. 4th edition. Edited by CA Burtis, ER Ashwood.
Philadelphia, WB Saunders Company, 1993, pp 1155-1235


