Bordetella pertussis Antibodies, IgA, IgG and IgM by ELISA with Reflex to Immunoblot
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
B. pertussis Ab, IgA by ELISA <=1.1 U/mL
B. pertussis Ab, IgG by ELISA 0.0 – 0.9 U/mL
B. pertussis Ab, IgM by ELISA <=1.1 U/mL
Recommend that treatment decisions be based on the result of the B. pertussis IgM immunoblot test instead of the ELISA test.
B. pertussis IgM test by ELISA may produce false-positive results.
Test Performed By: ARUP Laboratories
500 Chipeta Way
Salt Lake City, UT 84108
Detectable levels of IgG antibodies to B. pertussis may be seen in the
serum of vaccinated individuals of all ages, in early infancy as the result
of placental transfer, and in the convalescent phase of a recent infection.
IgG antibodies can only be used to diagnose active infection when paired
sera are available and a rise in antibody level can be demonstrated.
A significant rise may not always be demonstrated as peak levels of IgG
may be reached before the first sample is collected. Therefore, IgA and
IgM antibody levels should be measured to diagnose active disease.