Bordetella pertussis Antibodies, IgG and IgM by ELISA with Reflex to Immunoblot
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
B. pertussis Ab, IgG by ELISA <=2.4 U/mL
B. pertussis Ab, IgM by ELISA <=1.1 U/mL
Recommend that treatment decisions be based on the result of the B.pertussis IgM immunoblot instead of the ELISA test. B.pertussis IgM test by ELISA may produce false-positive results.
Test Performed By: ARUP Laboratories
500 Chipeta Way
Salt Lake City, UT 84108
Detectable levels of IgG antibodies to B. pertussis may be
seen in the serum of vaccinated individuals of all ages, in
early infancy as the result of placental transfer, and in
the convalescent phase of a recent infection. IgG antibodies
can only be used to diagnose active infection when paired
sera are available and a rise in antibody level can be
demonstrated. A significant rise may not always be demon-
strated as peak levels of IgG may be reached before the
first sample is collected. Therefore, IgA and IgM antibody
levels should be measured to diagnose active disease.