FSRP - Clinical: SRP

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Test ID: FSRP    

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.


Interpretation Provides information to assist in interpretation of the test results

Signal Recognition Particle (SRP) is a myositis specific autoantibody which is seen in 5-10% of adult and juvenile myositis. Symptoms often are acute onset of severe polymyositis with frequent myalgias, severe weakness and very high creatine kinase levels. Some adults experience cardiac involvement and palpitations. There is a poor response to therapy.