5368 - Clinical: Central Nervous System Consultation, Autopsy

Test Catalog

Test Name

Test ID: 5368    
Central Nervous System Consultation, Autopsy

Useful For Suggests clinical disorders or settings where the test may be helpful

Evaluation of congenital neurological disease


Evaluation of neurodegenerative disease


Evaluation of cases with a complex neurological or neurosurgical history


Evaluation of sudden unexplained death


Not for cases under litigation without preauthorization

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When only a brain is submitted, this test will be performed and charged.

When both a brain and spinal cord are submitted, 65094 / Central Nervous System with Spinal Cord Consultation, Autopsy (Bill Only) will be performed and this test (5368) will be credited.

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Difficult neurological abnormalities, including congenital anomalies, sometimes require the assistance of a neuropathologist. This evaluation is offered to provide the careful dissection and diagnostic experience that may be needed for unusual or rare neuropathological cases.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

This request will be processed as a consultation. Appropriate dissection will be performed and an interpretive report provided.

Interpretation Provides information to assist in interpretation of the test results

This request will be processed as a consultation. Appropriate stains will be performed and a diagnostic interpretation provided.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Specimens should be completely fixed in formalin for 7 to 10 days, prior to shipping.


It is best if specimen is not dissected prior to shipment.

Clinical Reference Provides recommendations for further in-depth reading of a clinical nature

1. Collins KA, Powers JM: Chapter 20: Autopsy procedures for the brain, spinal cord, and neuromuscular system. In Autopsy Performance and Reporting. Second edition. Edited by KA Collins, GM Hutchins GM. College of American Pathologists, 2003

2. Crain BJ, Mirra SS: Chapter 21: The autopsy in cases of Alzheimer's disease and other dementias. In Autopsy Performance and Reporting. Second edition. Edited by KA Collins, GM Hutchins. College of American Pathologists, 2003

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test