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Test ID: 5363
X-Ray Microanalysis

Useful For Suggests clinical disorders or settings where the test may be helpful

Useful for idenfitying elements within biological specimens. It

is the only technique that provides an in  situ means of

identifying elements within precise localized areas of thin

sections.

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

X-ray microanalysis is based on the principle that atoms, when

struck by a high energy electron beam, yields x-rays whose energy

is characteristic of those atoms. This, when coupled with an electron

microscope, allows for elemental as well as morphological analysis

of tissue and cell components.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

This request will be processed as a consultation. Appropriate

procedures will be performed and an interpretation provided.

Interpretation Provides information to assist in interpretation of the test results

Qualitative analysis can be performed simultaneously for all

elements in the periodic chart from boron (Z=4) through uranium

(Z=92).

 

Semiquantitative analysis may be possible in some cases.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

For accurate interpretation of data, proper specimen fixation

is critical.

 

The introduction of other elements may clutter the spectrum with

numerous unnecessary peaks making interpretation very difficult.

 

Not useful for identification of trace elements in a large volume

Clinical Reference Provides recommendations for further in-depth reading of a clinical nature

Ghadially FN:  Invited review.  The technique and scope of

electron-probe x-ray analysis in pathology.  Pathology

11:95-110, 1979.