Test ID: DPCP
Drug of Abuse, Phencyclidine Screen With GC-MS Confirmation, Urine
Useful For 
Suggests clinical disorders or settings where the test may be helpful
Detection of drug abuse involving PCP (angel dust or angel hair)
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Phencyclidine (PCP) is a drug of abuse. This compound affects diverse neural pathways and interacts with cholinergic, adrenergic, GABA-secreting, serotoninergic, opiate neuronal receptors, and gamma receptors. It has analgesic, anesthetic, and stimulatory effects, giving bizarre behavior, ranging from depression through catatonia, euphoria, violent rage, and hallucinations. Most fatalities result from its hypertensive effect.
Diagnosis of PCP usage depends on drug screen. PCP is excreted in the urine.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Negative
EMIT cutoff concentration: 25 ng/mL
Positives are reported with a quantitative GC-MS result.
Interpretation Provides information to assist in interpretation of the test results
The presence of PCP in urine at concentrations >10 ng/mL is a strong indicator that the patient has used PCP.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Urine PCP levels may be undetectable at alkaline pH.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
Baselt RC: In Disposition of Toxic Drugs and Chemicals in Man, 5th edition. Chemical Toxicology Institute, Foster City, CA 2000
External
link
PDF
document
Excel
document
Word
document