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Iodine is an essential element for thyroid hormone production. The measurement of urinary iodine serves as an index of adequate dietary iodine intake.
Monitoring iodine excretion rate as an index of daily iodine replacement therapy
Correlating total body iodine load with (131)I-uptake studies in assessing thyroid function
Daily urinary output <90 mcg/specimen suggests dietary deficiency.
Values >1,000 mcg/specimen may indicate dietary excess, but more frequently suggest recent drug or contrast media exposure.
Administration of iodine-based contrast media and drugs containing iodine, such as amiodarone, will yield elevated results.
0-15 years: not established
> or =16 years: 93-1,125 mcg/specimen
1. Knudsen N, Christiansen E, Brandt-Christensen M, et al: Age- and sex-adjusted iodine/creatinine ratio. A new standard in epidemiological surveys? Evaluation of three different estimates of iodine excretion based on casual urine samples and comparison to 24 h values. Eur J Clin Nutr 2000;54:361-363
2. Liberman CS, Pino SC, Fang SL, et al: Circulating iodine concentrations during and after pregnancy. J Clin Endocrinol Metab 1998;83:3545-3549