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Interpretive Handbook

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Test 90161 :
Growth Hormone-Releasing Hormone (GH-RH)

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Growth Hormone Releasing Hormone is a 44 amino acid peptide

produced primarily by the hypothalamus. It si a neurohumoral control

for adenohypophyseal secretion of Growth Hormone. Other

hypothalamic hormones have a stimulatory effect on pituitary hormones,

but Growth Hormone Releasing Hormone has no known effect on other

pituitary hormones. Somatostatin is the inhibitory counterpart of Growth

Hormone Releasing Hormone. Growth Hormone Releasing Hormone

has structural similarities with the Secretin-Glucagon family of

gastrointestinal hormones. Growth Hormone Releasing Hormone has

been isolated from pancreatic islet cells and various cancer tumor cells.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Levels of IR-GH-RH

  Baseline range:  5-18 pg/mL

Levels in GH-RH Dysfunction:

  Patients with acromegaly:  up to 200 pg/mL

  Patients with small cell lung carcinoma:  up to 50 pg/mL

  GH-RH secreting tumors:  200-10,000 pg/mL

 

This test was performed using a kit that has not been cleared or

approved by the FDA and is designated as research use only.

The analytic performance characteristics of this test have been

determined by Inter Science Institute. This test is not intended for

diagnosis or patient management decisions without confirmation

by other medically established means.

 

Test Performed by: Inter Science Institute

                                       944 West Hyde Park Blvd.

                                       Inglewood, CA 90302


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