Drug of Abuse Screen, DAU10, Urine
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
This test uses immunologic testing for drugs of abuse, by class, and screens for the presence of amphetamines, barbiturates, benzodiazepines, cocaine metabolite, methadone, opiates, phencyclidine, propoxyphene, tetrahydrocannabinol, and ethanol. Positive immunologic results are confirmed by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-tandem mass spectrometry (LC-MS/MS) with the exception of ethanol. Positive ethanol results are reported quantitatively directly from immunologic testing.
Detecting drug abuse involving amphetamines, barbiturates, benzodiazepines, cocaine, methadone, opiates, phencyclidine, propoxyphene, tetrahydrocannabinol, and ethanol
This test is intended to be used only by a qualified drug treatment counselor or physician.
A positive result indicates that the patient has used the drugs detected in the recent past.
For information about drug testing, including estimated detection times, see Drugs of Abuse Testing at http://www.mayomedicallaboratories.com/articles/drug-book/index.html
Creatinine and specific gravity are measured as indicators of specimen dilution.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
This technology exhibits a small (approximately 2%) false-positive rate due to the interaction of the reagents with naturally occurring substances and over-the-counter drugs.
This test does not screen for drug classes other than those listed above.
Note: Results are intended to be interpreted by a physician or health care professional. This test is not intended for use in employment-related testing.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
The specific drug identified will be reported.
EMIT cutoff concentrations
Amphetamines: 500 ng/mL
Barbiturates: 200 ng/mL
Benzodiazepines: 200 ng/mL
Cocaine (benzoylecgonine-cocaine metabolite): 150 ng/mL
Methadone: 300 ng/mL
Opiates: 300 ng/mL
Phencyclidine: 25 ng/mL
Propoxyphene: 300 ng/mL
THC: 50 ng/mL
Ethanol: 10 mg/dL
Results of this test are confirmed and should be considered definitive. Specimens are normally kept for 2 weeks after Mayo Medical Laboratories New England receipt date.
Clinical References Provides recommendations for further in-depth reading of a clinical nature
Porter WF, Moyer TP: Clinical toxicology. In Tietz Textbook of Clinical Chemistry. Fourth edition. Edited by CA Burtis, ER Ashwood. Philadelphia, PA, WB Saunders Company, 1993, pp 1155-1235