Angiotensin II, Plasma
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Angiotensin II is a eight amino acid peptide formed by Angiotensin
Converting Enzyme (ACE) cleavage of Angiotensin I. Angiotensin II
is metabolized further to Angiotensin III. Angiotensin II release is
controlled by Renin, blood pressure, blood volume, sodium balance
and by Aldosterone concentration. Levels of Angiotensin II are
increased in many types of hypertension. Angiotensin II stimulates
the release of Anti-Diuretic Hormone, ACTH, Prolactin, Luteinizing
Hormone, Oxytocin and Aldosterone. Angiotensin II increases
vasoconstriction and inhibits tubular resorption of sodium, and can
increase endothelial cell growth.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
10 - 60 pg/mL
This test was performed using a kit that has not been cleared or approved by the FDA and is designated as research use only. The analytic performance characteristics of this test have been determined by Inter Science Institute. This test is not intended for diagnosis or patient management decisions without confirmation by other medically established means.