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Interpretive Handbook

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Test 60590:
T- and B-Cell Quantitation and Lymphocyte Proliferation to Antigens and Mitogens Panel

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

See individual test IDs.

Useful For Suggests clinical disorders or settings where the test may be helpful

Assessing antigen-specific T-cell responses, global T-cell function, and quantitating lymphocyte subsets in a single orderable test.

 

This panel is most helpful when evaluating patients with immunodeficiencies, where quantitative decreases in T cells can lead to reduced functional antigen and/or mitogen responses.

 

See individual test IDs for additional information.

Interpretation Provides information to assist in interpretation of the test results

Since the presence of lymphopenia, particularly in the T-cell compartment, can reduce the magnitude of the proliferative response to both mitogens and antigens, it is helpful to perform simultaneous numerical evaluation of lymphocyte subsets to aid in interpretation of the functional (proliferation) data.

 

See individual test IDs for additional information.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

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Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

The appropriate age-related reference values will be provided on the report.

Clinical References Provides recommendations for further in-depth reading of a clinical nature

See individual test IDs.