|Values are valid only on day of printing.|
Pyrimidine 5' nucleotidase (P5'NT) is involved in the catabolism of RNA which is a normal constituent of reticulocytes but not of mature erythrocytes. A deficiency of P5'NT is evidenced by persistent reticulocytosis.
Workup of individuals with persistent reticulocytosis
Screening test negative for pyrimidine 5'nucleotidase deficiency
No significant cautionary statements
Fairbanks VF, Klee GG: Biochemical aspects of hematology. In Tietz Textbook of Clinical Chemistry. Third edition. Edited by CA Burtis, ER Ashwood, Philadelphia, WB Saunders Co., 1999, pp 1642-1647