Hematologic Disorders, Chromosome Hold, Bone Marrow or /Peripheral Blood
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Conventional chromosome analysis is the gold standard for identification of the common, recurrent chromosome abnormalities for most hematologic malignancies. Based on morphologic review of the bone marrow or peripheral blood specimen by a hematopathologist, a determination of additional appropriate testing can be made. If the specimen does not show evidence of malignancy, chromosome analysis may not be necessary. Depending on the diagnosis, FISH assays may also be more informative.
Holding the bone marrow or peripheral blood specimen in the laboratory but delay chromosome analysis while preliminary morphologic assessment is in process
If notified by the client, this test may be canceled and a processing fee assessed.
If no notification to cancel testing is received, this test will be reported as "reflexed for chromosome analysis" and depending on the specimen received, BM/8506 Chromosome Analysis, Hematologic Disorders, Bone Marrow or HBL/8537 Chromosome Analysis, Hematologic Disorders, Blood will be performed and an interpretive report provided.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
This test does not apply to any FISH assays. If specimen is to be held for FISH testing, HFH/7874 Hematologic Disorders, Fluorescence In Situ Hybridization (FISH) Hold, Bone Marrow or /Peripheral Blood must be ordered.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.