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Interpretive Handbook

Test 8482 :
Fibroblast Culture

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Cultures of skin fibroblasts are useful for specialized testing, which requires skin cells. These cells can be cultured and tested at Mayo Clinic or sent to external laboratories performing these specialized tests. In addition, cells are frozen for at least 3 years for potential future studies on cultured cells or for molecular genetic testing.

Useful For Suggests clinical disorders or settings where the test may be helpful

A preliminary step in obtaining cultured cells for genetic testing

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Potential interfering factors:

-Lack of viable cells

-Bacterial contamination

-Failure to transport tissue in an appropriate media

-Excessive transport time

-Exposure of the specimen to temperature extremes (freezing or >30 degrees C)

-Improper packaging may result in broken or leaky specimen containers or contamination of specimens during transport

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Not applicable

Clinical References Provides recommendations for further in-depth reading of a clinical nature

 


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