Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Many fungi in the environment cause disease in severely compromised human hosts. Accordingly, the range of potential pathogenic fungi has increased as the number of immunosuppressed individuals (persons with AIDS, patients receiving chemotherapy or transplant rejection therapy, etc.) has increased.
Few fungal diseases can be diagnosed clinically; most are diagnosed by isolating and identifying the infecting fungus in the clinical laboratory.
Detection of fungi in clinical specimens
Positive slides are reported as 1 or more of the following: yeast or hyphae present, organism resembling Blastomyces dermatitidis, Histoplasma capsulatum, Coccidioides immitis, Cryptococcus neoformans, or Malassezia furfur.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
No significant cautionary statements
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Clinical References Provides recommendations for further in-depth reading of a clinical nature
Lockhart SR, Diekema DJ, Pfaller MA: The epidemiology of fungal infections. In Clinical Mycology. Edited by EJ Anaissie, MR McGinnis, MA Pfaller. Second edition. Elsevier, Inc, 2009, pp 1-14