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Interpretive Handbook

Test 8335 :
Eosinophils, Urine

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Eosinophils are white blood cells that normally do not appear in urine. The presence of eosinophils in the urine is seen in acute interstitial nephritis, which is caused by an allergic reaction, typically to drugs.

Useful For Suggests clinical disorders or settings where the test may be helpful

Investigation of possible acute interstitial nephritis

Interpretation Provides information to assist in interpretation of the test results

Greater than 5% eosinophils indicates acute interstitial nephritis; 1% to 5% eosinophils is indeterminant.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

None seen

Clinical References Provides recommendations for further in-depth reading of a clinical nature

1. Hansel FK: In Clinical Allergy. CV Mosby Co. St. Louis, 1953

2. Brunzel NA: Chapter 8: Microscopic Examination of Urine Sediment. In Fundamentals of Urine and Body Fluids Analysis. Third edition. Edited by NA Brunzel. Elsevier Saunders. St. Louis, MO, 2012, pp 171-172