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Eosinophils are white blood cells that normally do not appear in urine. The presence of eosinophils in the urine is seen in acute interstitial nephritis, which is caused by an allergic reaction, typically to drugs.
Investigation of possible acute interstitial nephritis
Greater than 5% eosinophils indicates acute interstitial nephritis; 1% to 5% eosinophils is indeterminant.
No significant cautionary statements.
1. Hansel FK: In Clinical Allergy. CV Mosby Co. St. Louis, 1953
2. Brunzel NA: Chapter 8: Microscopic Examination of Urine Sediment. In Fundamentals of Urine and Body Fluids Analysis. Third edition. Edited by NA Brunzel. Elsevier Saunders. St. Louis, MO, 2012, pp 171-172