Comprehensive mtDNA Analysis by Massively Parallel Sequencing (MitoNGS)
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Zhang W, Cui H, Wong LJ. Comprehensive one-step molecular analyses of mitochondrial genome by massively parallel sequencing. Clin Chem. 2012,58:1322-31.
Scaglia F, Wong, LJ.Human mitochondrial tRNAs: role of pathogenic mutations in disease. Muscle Nerve 2008, 37:150-71.
Wong, LJ. Pathogenic mitochondrial DNA mutations in protein coding genes. Muscle Nerve 2007, 36:279-93.
Wong, LJ et al. Molecular and clinical genetics of mitochondrial diseases due to POLG mutations. Hum Mutat 2008, 29:E150-72.
Tang S, Wong LJ, et al. Mitochondrial DNA polymerase gamma mutations: an ever expanding molecular and clinical spectrum. J Med Genet 2011, 48 (10):669-81.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
A final report will be attached in Mayo Access.
Test Performed by: Baylor Medical Genetics Laboratories
2450 Holcombe Blvd.
Houston, TX 77021