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Interpretive Handbook

Test 90428 :
Angiotensin II, Plasma

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Angiotensin II is a eight amino acid peptide formed by Angiotensin

Converting Enzyme (ACE) cleavage of Angiotensin I. Angiotensin II

is metabolized further to Angiotensin III. Angiotensin II release is

controlled by Renin, blood pressure, blood volume, sodium balance

and by Aldosterone concentration. Levels of Angiotensin II are

increased in many types of hypertension. Angiotensin II stimulates

the release of Anti-Diuretic Hormone, ACTH, Prolactin, Luteinizing

Hormone, Oxytocin and Aldosterone. Angiotensin II increases

vasoconstriction and inhibits tubular resorption of sodium, and can

increase endothelial cell growth.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

10-60 pg/mL


This test was performed using a kit that has not been cleared or

approved by the FDA and is designated as research use only.

The analytic performance characteristics of this test have been

determined by Inter Science Institute. This test is not intended for

diagnosis or patient management decisions without confirmation

by other medically established means.


Test Performed By:  Inter Science Institute

                                        944 West Hyde Park Boulevard

                                        Inglewood, CA  90302