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Coagulation Testing Quality Conference

Coagulation Testing Quality
Conference and Wet Workshop


Coagulation Wet Workshop Overview

Tuesday, August 7, 2012

Following orientation presentations, participants will form teams for observing testing and discussing evaluation of “unknown” plasma specimens using coagulation instrumentation, reagents and technical specialists at each of four planned workstations. Testing will include prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), dilute Russell’s viper venom time (DRVVT), mixing tests using unknown and normal plasmas, platelet neutralization procedure (PNP) and other phospholipid-inhibitor confirmatory assays. Additional testing will include assays of fibrinogen, D-dimer and coagulation factor assays.

Workshop faculty will lead a discussion of results and interpretations, including comments about the clinical disorders studied and the comparability or diversity of results and interpretations obtained with different instruments or reagents.

Participation is limited to 80 registrants.

Learning Objectives

Upon completion of the workshop, participants should be able to:

  • Examine operation of contemporary coagulation instrumentation and reagents
  • Discern similarities and differences among coagulation reagents and instruments
  • Assess performance characteristics of different reagents and instruments for evaluating relatively common complex coagulopathies
  • Evaluate “screening tests” and “confirmatory tests” for detection, differentiation, and confirmation of differing coagulopathies
  • Explore “mixing tests” for differentiating inhibitors of coagulation from coagulation factor deficiencies
  • Discuss principles and performance of selected additional coagulation assays
  • Analyze the diagnostic sensitivity and specificity of results obtained with differing reagent instrument combinations and test procedures


Attendance at this Mayo Clinic workshop does not indicate nor guarantee competence or proficiency in the performance of any procedures that may be discussed or taught in this course. 

Intended Audience

This workshop is designed for laboratory technologists, physicians, and scientists who have responsibilities for diagnostic coagulation laboratory testing.

Educational Grants

This course is supported, in part, by educational grants in accordance with ACCME Standards.  A complete listing of commercial supporters will be provided to attendees at the program. Appropriate acknowledgment will be given to all supporters at the time of the meeting.