Tuesday, August 12, 2008

Description

Following orientation presentations, participants will form teams for testing and evaluation of four “unknown” plasma specimens using coagulation instrumentation, reagents and technical specialists at each of six workstations. Testing will include prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), dilute Russell’s viper venom time (DRVVT), mixing tests using unknown and normal plasmas, platelet neutralization procedure (PNP) and other phospholipid-inhibitor confirmatory assays. Additional testing will include assays of fibrinogen and selected coagulation factor activities (factors II, V, VIII, X). Workshop faculty will lead a discussion of results and interpretations, including comments about the clinical disorders studied and the comparability or diversity of results and interpretations obtained with different instruments or reagents. Participation is limited to 150 registrants.

Objectives

Upon completion of this workshop, participants should be able to:

• Examine operation of contemporary coagulation instrumentation and reagents
• Demonstrate similarities and differences among coagulation reagents and instruments
• Assess performance characteristics of different reagents and instruments for evaluating relatively common complex coagulopathies
• Evaluate “screening tests” and “confirmatory tests” for detection, differentiation, and confirmation of differing coagulopathies
• Explore “mixing tests” for differentiating inhibitors of coagulation from coagulation factor deficiencies
• Discuss principles and performance of coagulation factor activity assays
• Analyze the diagnostic sensitivity and specificity of results obtained with differing reagent instrument combinations and test procedures.

Intended Audience

This workshop is designed for laboratory technologists, physicians, and scientists who have responsibilities for diagnostic coagulation laboratory testing.

Credit

Mayo Medical Laboratories is approved as a provider of continuing education programs in the Clinical Laboratory Sciences by the ASCLS P.A.C.E.^® Program. This program has been approved for 7.0 P.A.C.E. contact hours. Level of instruction for this program is intermediate.

Mayo Medical Laboratories is approved as a Continuing Education Accrediting Agency for Clinical Laboratory Science for State of California and State of Florida credit. The level of instruction for this program is intermediate. This program has been approved for 7.0 contact hours.

Due to the nature of the workshop and the interaction from industry, Category 1 credit will not be provided for this one-day program.

Educational Grants
This course is supported, in part, by educational grants from coagulation-related diagnostics and therapeutics corporations. A complete listing of the commercial supporters for the Wet Workshop was not available when this site was posted but will be included in the Workshop Syllabus.

Date and Location
The Bleeding and Thrombosing Diseases Coagulation Wet Workshop will be held Tuesday, August 12, 2008. Course headquarters will be located in Heritage and Windsor Halls on the lower level of The Kahler Grand Hotel, 20 Second Avenue SW, Rochester, Minnesota. Registration and breakfast as well as Workshop Orientation Session will be held in the Elizabethan Room, main level of The Kahler Grand Hotel. Laboratory Testing will be held in Heritage and Windsor Halls. And the Data Review and Discussion Session will be held in Phillips Hall, Mayo Clinic Siebens Education Building that is adjacent to the Kahler Grand Hotel and connected by pedestrian subway and skyway.