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Test Utilization Resources for Clinicians

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What are Hot Topics?

Hot Topics are presentations by Mayo Clinic laboratory professionals and are focused on laboratory topics and test utilization.

Most also include Beyond Hot Topics, which are a compilation of questions asked by viewers and answers provided by the presenter.

Hot Topics are available in a number of formats to fit your needs; view the recorded presentations, print and/or read the transcript, or download the podcast.

How do I use Hot Topics?

Knowledge gained from Hot Topics should be shared with clinicians in an effort to decrease inappropriate test orders and offer solutions to help reduce test-ordering errors to improve patient care and reduce costs.

How Can I Share Hot Topics with Colleagues?

This information can be shared with colleagues by clicking the “email page” button at the top of each page.

Hot Topics

Piero Rinaldo, MD, PhD

The Region 4 Stork (R4S) Collaborative Project, Part 1: Laboratory Quality Improvement of Newborn Screening

Newborn screening has been very successful in identifying newborns with classic syndromes. However, many newborns have complex metabolic profiles that are difficult to interpret, leading to false-positives and missed diagnoses. To improve detection of true-positives, the Regional Genetics Collaborative project, funded by the Health Resource and Service Administration, has created the Region 4 Collaborative Stork project, which uses Mayo-developed software for postanalytical interpretation of complex metabolic profiles.

Part 1 introduces the concept of disease ranges for improved identification of abnormal newborn screening results.

A 6-part presentation by Piero Rinaldo, MD, PhD


Published on May 15, 2013View presentation...

Hot Topics

Kaaren Reichard, MD

Acute Promyelocytic Leukemia with t(15;17)(q24;q21); PML-RARA

Acute promyelocytic leukemia (APL) with t(15;17)(q24;q21); PML-RARA comprises 5% to 10% of all acute myelogenous leukemia (AML) cases. APL can often be differentiated from other types of AML based on bone marrow morphology, but the genetic aberration is diagnostic of APL regardless of blast percentage. Cytochemistry, flow cytometry, conventional cytogenetics and PML-RARA identification by RT-PCR and FISH are all important laboratory assays for the diagnosis of APL.

A presentation by Kaaren Reichard, MD


Published on May 1, 2013View presentation...

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