Autoimmune Dysautonomia Evaluation

Pandysautonomia

July 2012

Pandysautonomia usually occurs subacutely in onset in an autoimmune context and is usually severe and affects multiple systems. Symptoms and signs include an impaired papillary light reflex, loss of sweating, orthostatic hypotension leading to dizziness and syncope on standing up or sometimes sitting up, cardiac arrhythmias may occur, gastrointestinal dysmotility such as early satiety and vomiting, small bowel pseudo-obstruction and severe constipation may occur. The patients may also complain of dry eyes and dry mouth known as "sicca symptoms." Patients may develop bladder dysfunction.

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Jump to section:

• Introduction
• New Profile
• Autoimmune Dysautonomia
• Autoimmune Dysautonomia
• Autoimmune Dysautonomia^1,2
• Pandysautonomia
• Limited Dysautonomia³
• Objective Testing
• Thermoregulatory Sweat Testing: Measuring Heat-Induced Sweating
• Antibody Testing in Autoimmune Dysautonomia
• Antibody Testing in Autoimmune Dysautonomia
• Ganglionic Acetylcholine Receptor (AChR) Autoantibody
• Ganglionic AChR Autoantibody
• Autoimmune Dysautonomia Antibody Profile
• ADE/89904 Autoimmune Dysautonomia Evaluation, Serum Algorithm
• ADE/89904 Autoimmune Dysautonomia Evaluation, Serum Algorithm
• ADE/89904 Autoimmune Dysautonomia Evaluation, Serum Algorithm
• ADE/89904 Autoimmune Dysautonomia Evaluation, Serum Algorithm
• Clinical Utility of Autoimmune Dysautonomia Evaluation
• Clinical Utility of Autoimmune Dysautonomia Evaluation
• Summary
• References
• Questions