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The Use of Genetics in Guiding Therapy


Slide 13

June 2012

Warfarin is one of the most commonly prescribed drugs. It is an anticoagulant used for the short- and long-term management of thromboembolic disorders. Warfarin can be challenging to dose appropriately, and the prothrombin time, or INR, of warfarin must be maintained in a narrow therapeutic range. If an individual is given too much warfarin, they can have an elevated INR and be at risk for major bleeding complications. If an individual is not given enough warfarin, they can have subtherapeutic levels and be at risk for thrombotic complications.



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