Autoantibody Profiles Of Myasthenia Gravis, Thymoma, and Lambert-Eaton Myasthenic Syndrome

Autoantibodies Detected in MG Patients With Thymoma

May 2012

These and other antibody tests are positive in patients with thymoma, as well as myasthenia gravis. Acetylcholine receptor binding antibody in 100%, acetylcholine receptor modulating antibody in 99%, striational antibodies in 76%, neuronal antibodies in 43% including antibodies targeting voltage-gated potassium channels, CRMP-5, ganglionic alpha-3 acetylcholine receptor and GAD65.

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Autoantibodies in Patients With Thymoma

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Jump to section:

• Introduction
• Serological Diagnostic Algorithms
• 'Hot Topic' Points
• What are MG and LES?
• What are MG and LES?
• MG: Clinical Diagnosis
• MG: Neoplastic Accompaniments
• LES: Clinical Diagnosis
• LES: Electromyography (EMG) Findings
• LES: Neoplastic Accompaniments
• Autoantibodies Aiding MG Diagnosis
• Autoantibodies Aiding MG Diagnosis
• Single Assay Detects AChR Modulating and AChR Blocking Antibody
• Serum AChR Modulating Antibody Values and Interpretation
• Reasons to Discontinue Testing for AChR Blocking Antibody
• Striational Antibodies
• Autoantibodies Detected in MG Patients With Thymoma
• Autoantibodies Aiding the Diagnosis of LES
• Autoantibodies Aiding the Diagnosis of LES
• MGEA/83370 Myasthenia Gravis (MG) Evaluation, Adult Algorithm
• MGEP/83371 Myasthenia Gravis (MG) Evaluation, Pediatric Algorithm
• MGETH/83372 Myasthenia Gravis (MG) Evaluation, Thymoma Algorithm
• MGLES/83369 Myasthenia Gravis (MG)/Lambert-Eaton Syndrome (LES) Algorithm
• Summary
• Questions?