Autoantibody Profiles Of Myasthenia Gravis, Thymoma, and Lambert-Eaton Myasthenic Syndrome

Autoantibodies Aiding MG Diagnosis

May 2012

Autoantibodies aiding the diagnosis of myasthenia gravis include the acetylcholine receptor binding antibody, modulating antibody, and striational antibody. The binding antibody distinguishes acquired from congenital myasthenia gravis, raises the question of subclinical myasthenia gravis in thymoma patients. There is a low but significant frequency in other autoimmune neurological disorders including Lambert-Eaton syndrome, peripheral neuropathies, encephalopathies, radiculopathies, and myelopathies.

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Autoantibodies Aiding MG Diagnosis

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Jump to section:

• Introduction
• Serological Diagnostic Algorithms
• 'Hot Topic' Points
• What are MG and LES?
• What are MG and LES?
• MG: Clinical Diagnosis
• MG: Neoplastic Accompaniments
• LES: Clinical Diagnosis
• LES: Electromyography (EMG) Findings
• LES: Neoplastic Accompaniments
• Autoantibodies Aiding MG Diagnosis
• Autoantibodies Aiding MG Diagnosis
• Single Assay Detects AChR Modulating and AChR Blocking Antibody
• Serum AChR Modulating Antibody Values and Interpretation
• Reasons to Discontinue Testing for AChR Blocking Antibody
• Striational Antibodies
• Autoantibodies Detected in MG Patients With Thymoma
• Autoantibodies Aiding the Diagnosis of LES
• Autoantibodies Aiding the Diagnosis of LES
• MGEA/83370 Myasthenia Gravis (MG) Evaluation, Adult Algorithm
• MGEP/83371 Myasthenia Gravis (MG) Evaluation, Pediatric Algorithm
• MGETH/83372 Myasthenia Gravis (MG) Evaluation, Thymoma Algorithm
• MGLES/83369 Myasthenia Gravis (MG)/Lambert-Eaton Syndrome (LES) Algorithm
• Summary
• Questions?