Dengue Fever

Laboratory Confirmation of Dengue

May 2012

Finally, the plaque reduction and neutralization assay, the PRNT assay, is the most specific serologic tool for the detection of dengue.

This test will subtype dengue infections, and measures titer of neutralizing antibodies. It is labor intensive and requires maintenance of very specific cell lines, thus it is primarily limited to research laboratories and certain state health departments. The CDC website listed on the slide gives a up-to-date overview of available dengue tests, which you may find helpful.

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Laboratory Confirmation of Dengue

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Jump to section:

• Introduction
• Overview
• Dengue Virus
• Structure of Dengue Virus
• History
• History
• Epidemiology of Dengue
• Vectors of Dengue
• Vectors of Dengue
• Life Cycle of Dengue Virus
• Pathogenesis of Dengue
• Classification of Dengue Disease
• Antibody-Dependent Enhancement (ADE)
• Symptoms of Dengue
• Severe Dengue
• Treatment of Dengue
• Diagnosis of Dengue
• Diagnostic Markers for Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Rapid Tests
• Laboratory Confirmation of Dengue
• Future Considerations
• Why Are We Concerned About Dengue?
• Key West, Florida 2009–2010
• Key West, Florida 2009–2010
• Why Re-emergence of Dengue in Florida?
• Summary
• Summary
• Summary
• Summary
• References
• Questions