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Dengue Fever



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Pathogenesis of Dengue

Slide 11

May 2012

In the human host, after a bite, the virus infects immature dendritic cells of immune system.

The infected dendritic cells then migrate to the lymph nodes with activation of the cellular and humoral immune response.

Viral replication occurs in macrophages of lymph nodes, liver, spleen, parenchymal cells, as well as peripheral blood monocytes.

The host will then become viremic within 3 to 6 days.

Pathogenesis of Dengue

 


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