Dengue Fever

History

May 2012

This is an engraving is from the National Library of Medicine of Dr. Benjamin Rush. Not only was he a signatory of the Declaration of Independence, but a professor of chemistry and medical theory at the University of Pennsylvania.

During the Philadelphia epidemic of 1779–1780, Dr. Rush first described the dramatic symptoms of dengue as "Breakbone Fever."

Jump forward to the late 1930s, where WWII facilitated spread of dengue through Asia/Pacific region. Approximately 80,000 military personnel serving in the Pacific theater were diagnosed with dengue between 1942 and 1945.

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Jump to section:

• Introduction
• Overview
• Dengue Virus
• Structure of Dengue Virus
• History
• History
• Epidemiology of Dengue
• Vectors of Dengue
• Vectors of Dengue
• Life Cycle of Dengue Virus
• Pathogenesis of Dengue
• Classification of Dengue Disease
• Antibody-Dependent Enhancement (ADE)
• Symptoms of Dengue
• Severe Dengue
• Treatment of Dengue
• Diagnosis of Dengue
• Diagnostic Markers for Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Laboratory Confirmation of Dengue
• Rapid Tests
• Laboratory Confirmation of Dengue
• Future Considerations
• Why Are We Concerned About Dengue?
• Key West, Florida 2009–2010
• Key West, Florida 2009–2010
• Why Re-emergence of Dengue in Florida?
• Summary
• Summary
• Summary
• Summary
• References
• Questions