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Viral Culture

Uses and Pitfalls

Shell Vial Culture

Slide 9

April 2012

Shell vial culture is a modification of the tube culture. It uses a smaller tube containing a coverslip and it is actually the coverslip that contains the cell monolayer. You can see an example of a shell vial and the coverslip it contained on the right. Shell vials are commercially available. Some even contain more than 1 type of cell. When using a shell vial culture, the cell layer is first inoculated with specimen.

Shell Vial Culture


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