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HPV and p16 Testing in Oropharyngeal Squamous Cell Carcinoma

Methodology, Interpretation, and Significance



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Introduction

Slide 1

March 2012


Welcome to Mayo Medical Laboratories' Hot Topics. These presentations provide short discussions of current topics and may be helpful to you in your practice.

Our presenter for this program is Dr. Joaquín García from the Division of Anatomic Pathology in the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, Minnesota. Dr. García will describe the role of human papillomavirus and p16 in the pathogenesis of oropharyngeal squamous cell carcinoma and discuss indications for and interpretation of testing for HPV and p16. Thank you Dr. García.

Thank you for the kind introduction. It is an honor and a privilege to speak to you on a topic that promises to change the way we view the biology and management of head and neck cancer in the coming years. My intent today is to package the current understanding of HPV and p16 testing, interpretation, and significance in the context of oropharyngeal squamous cell carcinoma in a useable way for head and neck practitioners; that is, laboratory technicians, investigators, pathologists, surgeons, and oncologists.

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