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HPV and p16 Testing in Oropharyngeal Squamous Cell Carcinoma

Methodology, Interpretation, and Significance



Outline

Slide 3

March 2012

I will attempt to look at this issue with a wide angle lens, focusing on principles and phenomena rather than inundating you with a deluge of references and statistics. Although I will certainly mention some of the more important studies and statistics, anyone driven to learn more about this topic is strongly encouraged to browse the references listed at the conclusion of this presentation.

To this end, we will start with a review of oropharyngeal squamous cell carcinoma - followed by a discussion regarding our current understanding of HPV’s and p16’s role in oropharyngeal squamous cell carcinoma. We will then transition into indications for HPV and p16 testing in oropharyngeal squamous cell carcinoma. At least equally as important, we will spend time discussing the idiosyncrasies of HPV and p16 test interpretation in oropharyngeal squamous cell carcinoma. Finally, we will wrap up with a review of the salient features of HPV and p16 testing in this context.

Outline

 


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