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Clopidogrel Platelet Function Tests

Caveats and Controversies



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Clopidogrel Genetics (Cont'd)

Slide 29

December 2011

Several medications are also metabolized by the CYP2C19 enzyme and would be affected by these CYP2C19 gene polymorphisms as well. Prasugrel, like clopidogrel, is a prodrug converted in the liver to the active metabolite, but prasugrel uses multiple different CYP enzymes and thus is not affected by the polymorphisms of the CYP2C19 gene.

Clopidogrel Genetics (Cont'd)

 


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