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Clopidogrel Platelet Function Tests

Caveats and Controversies


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Slide 18

December 2011

The PFA-100 is designed to measure platelet adhesion and aggregation under high shear conditions, mimicking injured endothelium. The time necessary to block a membrane coated in either collagen and epinephrine or collagen and ADP is measured and called the closure time. The collagen/ADP cartridge would be the one used for P2Y12 antagonist testing.



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