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Clopidogrel Platelet Function Tests

Caveats and Controversies


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VerifyNow P2Y12 Test

Slide 14

December 2011

The results are given as three numbers. The first number is a measure of the patient’s platelet function in the presence of clopidogrel. The second number measures activation of the patient’s platelets independently of the P2Y12 receptor using 2 reagents within a second channel. The last number calculates the percent inhibition of the patient’s platelets by clopidogrel using the first two numbers. Less than twenty to thirty percent inhibition of platelet activation is considered to be resistance to clopidogrel. Some studies and institutions use values over 235 P2Y12 Reaction Units (PRU) as indicative of clopidogrel resistance.

VerifyNow P2Y12 Test


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