Evaluation of Prosthetic Implant Degradation

Introduction

December 2011

Welcome to Mayo Medical Laboratories' Hot Topics. These presentations provide short discussions of current topics and may be helpful to you in your practice.

Our presenters for this program are from Mayo Clinic in Rochester, Minnesota. Dr. Rafael J. Sierra is Associate Professor of Orthopedics and Consultant in the Division of Orthopedic Surgery and Dr. Thomas Moyer is Professor of Laboratory Medicine and Consultant in the Division of Clinical Biochemistry and Immunology. Dr. Sierra will discuss the clinical aspects of metal-on-metal hip implants and Dr. Moyer will explain the role of serum chromium and cobalt in evaluating prosthetic implant degradation

Thank you, Sharon, for that introduction.

Introduction

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Jump to section:

• Orthopedic Prostheses
• Background
• Patient Workup
• Issues of Concern
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Effect of Metallosis
• Initial Conclusions
• Interpretive Values
• Are These Concentrations Toxic?
• Are These Concentrations Toxic?
• Specimen Collection
• Metal-Free Blood Tubes
• Summary
• References/Additional Reading
• Questions?
• Disclosure (Dr. Sierra)
• Disclosure (Dr. Moyer)