Evaluation of Prosthetic Implant Degradation

Disclosure (Dr. Sierra)

December 2011

I have significant financial relationships with companies and these companies make metal-on-metal hip replacements. I am a consultant for Biomet and our department obtains research support from DePuy, Stryker, and Zimmer.

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Disclosure (Dr. Sierra)

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Jump to section:

• Introduction
• Orthopedic Prostheses
• Background
• Patient Workup
• Issues of Concern
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Effect of Metallosis
• Initial Conclusions
• Interpretive Values
• Are These Concentrations Toxic?
• Are These Concentrations Toxic?
• Specimen Collection
• Metal-Free Blood Tubes
• Summary
• References/Additional Reading
• Questions?
• Disclosure (Dr. Sierra)
• Disclosure (Dr. Moyer)