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Evaluation of Prosthetic Implant Degradation

Orthopedic Prostheses



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Summary

Slide 15

December 2011

In summary, serum chromium and cobalt are elevated in all patients with metal-on-metal orthopedic implants as compared to unexposed individuals. Serum concentrations increase with implant duration, even in patients with no significant implant wear. The degree of elevation of serum chromium and cobalt correlates with metal-on-metal orthopedic implant deterioration. Elevated serum chromium and cobalt in the absence of symptoms such as joint pain or unsteady gait do not, independently, indicate implant wear. And, proper specimen collection is essential for successful evaluation.

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