Evaluation of Prosthetic Implant Degradation

Metal-on-Metal Wear-Induced Tissue Necrosis

December 2011

The junction of the acetabular cup and femoral head is exposed to tremendous pressure during motion; this joint bears the total body weight. In the case of metal-on-metal wear, these surfaces can deteriorate, generating micro-particles of metal. These metal particles can become integrated into the soft tissue surrounding the implant, leading to necrosis. These metal particles also undergo corrosion, allowing metal ions to enter and circulate in blood serum. Now, Dr. Thomas Moyer, will continue with our discussion.

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Jump to section:

• Introduction
• Orthopedic Prostheses
• Background
• Patient Workup
• Issues of Concern
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Metal-on-Metal Wear-Induced Tissue Necrosis
• Effect of Metallosis
• Initial Conclusions
• Interpretive Values
• Are These Concentrations Toxic?
• Are These Concentrations Toxic?
• Specimen Collection
• Metal-Free Blood Tubes
• Summary
• References/Additional Reading
• Questions?
• Disclosure (Dr. Sierra)
• Disclosure (Dr. Moyer)